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Key Recommendations on Alcohol in the Dietary Guidelines for Americans:

The Dietary Guidelines does not recommend that individuals who do not drink alcohol start drinking for any reason.

If adults age 21 years and older choose to drink alcoholic beverages, drinking less is better for health than drinking more.
Evidence indicates that, among those who drink, higher
average alcohol consumption is associated with an increased risk of death from all causes compared with lower average alcohol consumption. Alcohol misuse or consuming alcohol in excess of recommendations increases risk of several other conditions such as liver disease, cardiovascular disease, injuries, and alcohol use disorders.
For the purposes of evaluating amounts of alcohol that
may be consumed, the Dietary Guidelines defines drink
equivalents. One alcoholic drink equivalent is defined as
containing 14 grams (0.6 fl oz) of pure alcohol.
The following count as one alcoholic drink equivalent:

12 fluid ounces of regular beer (5% alcohol), 5 fluid
ounces of wine (12% alcohol), or 1.5 fluid ounces of 80 proof distilled spirits (40% alcohol). To help Americans move toward a healthy dietary pattern and minimize risks associated with drinking, adults of legal drinking
age can choose not to drink or to drink in moderation
by limiting intakes to 2 drinks or less in a day for men and 1 drink or less in a day for women, on days when alcohol is consumed. This is not intended as an averageover several days, but rather the amount consumed on any single day. Binge drinking,3 defined as 5 or more drinks for the typical adult male or 4 or more drinks for the typical adult female in about 2 hours, should be avoided. Emerging evidence suggests that even drinking within the recommended limits may increase the overall risk of death from various causes, such as from several types of cancer and some
forms of cardiovascular disease. Alcohol has been
found to increase risk for cancer, and for some types of cancer, the risk increases even at low levels of alcohol consumption (less than 1 drink in a day). Caution, therefore, is recommended.
Alcoholic beverages are not a component of the
USDA Dietary Patterns. The amount of alcohol and calories in beverages varies and should be accounted
for within the limits of healthy dietary patterns, so
that calorie limits are not exceeded.

There are many circumstances in which people should not drink alcohol:

There are also some people who should not drink at all, such as if they are pregnant or might be pregnant; under the legal age for drinking; if they have certain medical conditions or are taking certain medications that can interact with alcohol; and if they are recovering from an alcohol use disorder or if they are unable to control the amount they drink.

Review full text at dietaryguidelines.gov/sites/default/files/2021-03/Dietary_Guidelines_for_Americans-2020-2025.pdf