From: dragonw@mindspring.com
Sent: Friday, March 22, 2002 4:02 PM
Subject: Wine question
I've heard much about the health benefits of wine. Are these
same benefits
not present or less present in grape juice or raw grapes?
Thank you for your email.
Grapes and grape juice contain important constituents that are
also present in wine- namely antioxidants ( resveratrol and quertecin
and trace elements such as boron, iron and vitamin complexes that
are important to our health. In relation to our biggest killer
in the western world - namely heart disease - it is the alcohol
itself which is important in wine - or in any alcoholic beverage.
PLease read the summary below by Professor R Curtis Ellison of
Harvard Medical school - it is an effective summary:
Scientists have identified many mechanisms by which alcoholic
beverages reduce the risk of coronary heart disease. The most-studied
effect is on the levels of blood cholesterol. Any type of alcoholic
beverage lowers the LDL-cholesterol (the "bad cholesterol") slightly;
but even more importantly, markedly increases the levels of HDL-cholesterol,
the "good cholesterol."
Moderate drinkers are also less likely to form clots within the
arteries to the heart (leading to a myocardial infarction), to
the brain (leading to stroke), and to other organs. Part of the
protection against blood clots relates to the effects of alcohol
and wine on decreasing the "stickiness" of blood platelets (a
function similar to aspirin); platelets tend to aggregate and
lead to clots within arteries and enhance the development of atherosclerosis
and myocardial infarction. The decrease in clotting is related
both to alcohol and to non-alcoholic substances present in certain
beverages, especially red wine and dark beers. Many of the effects
on clotting are transient effects, and the beneficial effects
may last only for 24-36 hours after someone has consumed alcohol.
Much of the protection against heart disease of the French may
relate to their pattern of consuming wine with meals every day.
Drinking only on the weekend, especially "binge drinking," is
an unhealthy way to drink.
The scientific literature is increasingly demonstrating that alcohol
and/or red wine have numerous other effects that relate to the
development of atherosclerosis or heart disease. Some of these
effects are due to antioxidants, particularly high in red wine,
that decrease the oxidation of the harmful LDL-cholesterol; oxidation
makes LDL more likely to be incorporated into the vessel wall
and lead to atherosclerosis. Further, alcohol and wine are now
known to have favorable effects directly on the lining of blood
vessels, the vascular endothelium, which is intimately involved
in the development of atherosclerosis and heart disease. While
heavy drinkers tend to be more likely to develop hypertension
(high blood pressure), itself an important risk factor for coronary
disease, it is now known that light-to-moderate drinkers have
no increase in the risk of hypertension, and may actually have
a small reduction in blood pressure. Other potentially important
effects of alcoholic beverages are improvements in glucose metabolism:
moderate drinkers are less likely to develop diabetes, and diabetics
who drink moderately are less likely to have a heart attack. Another
factor in the protection from alcohol and wine relates to their
inhibition of inflammation, which is now realized to be an important
factor in the development of atherosclerosis.
Beneficial Effects of Moderate Drinking on Non-vascular Diseases
Diabetes is a major health problem in the United States, and around
the world, primarily because of increasing obesity. As stated
above, several studies have demonstrated that moderate drinkers
are less likely to develop diabetes. Another common disease associated
with aging is osteoporosis, which frequently leads to hip fractures
in the elderly. In many studies, moderate drinking increases bone
mineral density, and reduces the risk of osteoporosis and hip
fracture.
Other diseases shown to occur less frequently in moderate drinkers
than in abstainers include gall bladder disease and kidney stones.
But the most exciting recent scientific findings are that moderate
drinkers have lower rates than abstainers of Alzheimers Disease
and dementia. Studies in the Framingham Study, and from France,
Holland, Australia, and elsewhere, have documented that moderate
drinkers tend to perform better on tests of memory and cognitive
functioning, and are less likely to develop dementia. The mechanisms
for such protection are not known, but may relate to prevention
of atherosclerosis in the blood vessels supplying the brain. So
instead of alcohol increasing the risk of becoming demented, the
risk is apparently reduced in people who consume alcohol moderately.
I hope this answers your query - do email back if you have further
questions.
Yours sincerely,
Helena Conibear
Editorial Director
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